R&D PhD Chemist
Our client are seeking to recruit a PhD Chemist, on a 12 month fixed term contract.
This position is based at the R&D Centre in North Dublin. The R&D Centre has co-located technical and operational expertise, including analytical and engineering expertise that supports the development and manufacture of clinical and commercial products (small molecule APIs).
The R&D Chemist will be responsible for providing support for all aspects of new and existing chemical processes development, technology transfer, process scale-up, process safety, process monitoring, and process troubleshooting for small molecules. The role will involve cross functional collaboration with other functions including R&D, manufacturing, Quality, EHS and external stakeholders working towards existing and new product introduction and ensuring all processes are understood, robust, efficient and in control.
Key responsibilities of the role:
- Coordinate tech transfer activities for introduction of new clinical and commercial products to the site, including process development in the laboratory, customer engagement, troubleshooting, documentation, and campaign readiness.
- Lead development and optimization projects in the laboratory, including route scouting and route development, proof of concept, process safety assessment, particle engineering and powder properties characterization.
- Support chemistry assessments for new products as required.
- Provide technical support to the manufacture of APIs and intermediates manufactured at SK biotek Ireland, with a focus on optimization and investigation support.
- Lead optimization projects on throughput and yield in collaboration with R&D engineers.
- Support continuous process verification through collection and trending of data for commercial products, identifying Out of Trends (OOT) and Statistical Alert Events (SAE) and leading investigations where required with support from R&D engineers and analytical chemists.
- Actively participate in manufacturing campaign performance support teams.
- Lead and support quality and safety investigations.
- Identify and implement new technologies for the R&D laboratories to support new products and the business needs of the site.
- Collaborate with R&D engineers and R&D analytical chemists on new products introduction and scale up activities.
Required Key Skills and Experience:
- Strong technical background in chemistry.
- PhD in organic chemistry.
- 2+ years of experience in the Pharmaceutical business
- Strong interpersonal and communicational skills and demonstrated ability to work across a matrix.
- Excellent problem solving skills and commitment to continuous improvement.
- Expertise in organic chemistry, process development, project management, troubleshooting and continuous process verification.
- Demonstrated capability in the use of standard tools for root cause analysis and standard statistical tools.
- Demonstrated capability in the use of various analytical/diagnostic tools including PAT, chromatography and process safety.
- Ensure that GMP, Quality, Health & Safety are considered in all aspects of the role.
If you are interested in the role please click 'apply', otherwise contact Dominic on 01-6455254 for further information.
Only candidates with a current valid Irish work visa will be considered for this role.
